MIT NEWS (FEBRUARY 5 , 2004)
MIT neuroscientists have discovered a new brain mechanism controlling the formation of lasting memories.
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Long-lasting memories are stored in the brain through strengthening of the connections, or synapses, between neurons.
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"What we have discovered that hasn't been established before is that there is a direct activational signal from the synapse to the protein synthesis machinery," said Tonegawa, the Picower Professor of Biology and Neuroscience in MIT's Departments of Brain and Cognitive Sciences and Biology.
The central component of this pathway, an enzyme called "mitogen-activated protein kinase" (MAPK), effectively provides a molecular switch that triggers long-term memory storage by mobilizing the protein synthesis machinery.
(...)
Long-lasting memories are stored in the brain through strengthening of the connections, or synapses, between neurons.
(...)
"What we have discovered that hasn't been established before is that there is a direct activational signal from the synapse to the protein synthesis machinery," said Tonegawa, the Picower Professor of Biology and Neuroscience in MIT's Departments of Brain and Cognitive Sciences and Biology.
The central component of this pathway, an enzyme called "mitogen-activated protein kinase" (MAPK), effectively provides a molecular switch that triggers long-term memory storage by mobilizing the protein synthesis machinery.
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